0001678660 2025-08-14 2025-08-14 false 0001678660 8-K 2025-08-14 Prelude Therapeutics Incorporated DE 001-39527 81-1384762 175 Innovation Boulevard Wilmington DE 19805 (302) 467-1280 false false false false Common Stock, $0.0001 par value per share PRLD NASDAQ true false