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Weighted average exercise price per share, Granted Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Exercise Price Range Exercise Price Range [Axis] Shelf Registration statement expiration period Registration Payment Arrangement, Expiration Period Registration payment arrangement, expiration period. Potential sales milestone Potential Sales Milestone Potential sales milestone. Financial Instrument [Axis] Weighted average remaining contractual term (years), Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Net Loss Per Share Earnings Per Share, Policy [Policy Text Block] General and Administrative General and Administrative Expense [Member] Voting Common Stock Voting Common Stock [Member] Voting common stock. Revenue Recognition Revenue [Policy Text Block] Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Share-Based Payment Arrangement [Abstract] Stock-based compensation expense Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture, Total Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture 2021 Shelf Registration Two Thousand Twenty One Shelf Registration [Member] Two thousand twenty one shelf registration. Schedule of Future Minimum Annual Lease Payments Under Operating and Finance Lease Lessee, Operating Lease Liability And Finance Lease Liability, to be Paid, Maturity [Table Text Block] Lessee, operating lease liability and finance lease liability, to be paid, maturity. Upfront payment Upfront Payment Upfront payment. Accounting Policies [Abstract] Summary of Stock Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] 2024 (remaining) Finance Lease, Liability, to be Paid, Remainder of Fiscal Year Stockholders’ equity: Equity, Attributable to Parent [Abstract] Cash, Cash Equivalents and Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Statement [Table] Statement [Table] Property and equipment in accounts payable and accured expenses and other currents liabilites. Property and Equipment in Accounts Payable and Accured Expenses and Other Currents Liabilites Property and equipment in accounts payable and accrued expenses and other current liabilities Reimbursements for development of lab space previous expiration year Reimbursements For Development Of Lab Space Previous Expiration Year Reimbursements for development of lab space previous expiration year. Entity File Number Securities Act File Number Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Net increase (decrease) in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Jefferies LLC. Jefferies LLC [Member] Jefferies LLC Per share information: Earnings Per Share [Abstract] Cash Equivalents Cash Equivalents [Member] Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation [Table] Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Lease Contractual Term Lease Contractual Term [Domain] Statement of Financial Position [Abstract] Operating Lease, until December 31,2023 Operating Lease Until June302023 [Member] Operating lease, until June 30, 2023. 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Issuance of common stock upon exercise of stock options & vesting of RSUs, (shares) Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Exercisable, Ending Balance Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Exercisable, Beginning Balance Options Exercisable, Number Exercisable Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Exercisable Entity Tax Identification Number Entity Tax Identification Number Assets Assets [Abstract] Class of Warrant or Right [Domain] Grant received for increasing job Grant Received for Increasing Jobs Grant received for increasing jobs. Entity Current Reporting Status Entity Current Reporting Status Weighted average remaining contractual term (years), Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term 2028 Finance Lease, Liability, to be Paid, Year Four Registration Payment Arrangement, Arrangement [Domain] Subsequent Events [Abstract] Schedule of Accrued Expenses and Other Current Liabilities Schedule Of Accrued Expenses And Other Current Liabilities Table [Text Block] Schedule of accrued expenses and other current liabilities. Document Fiscal Year Focus Document Fiscal Year Focus Change in accounting principle, ASU, adoption date Change in Accounting Principle, Accounting Standards Update, Adoption Date Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Cash, cash equivalents, and restricted cash at beginning of period Cash, cash equivalents, and restricted cash at end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations City Area Code City Area Code Total current liabilities Liabilities, Current Local Phone Number Local Phone Number Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Rent expense. Rent Expense Rent expense Income taxes Income Tax, Policy [Policy Text Block] Commitments and Contingencies Disclosure [Abstract] Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Marketable securities, Amortized cost Debt Securities, Available-for-Sale, Amortized Cost $4.57 - $5.13 Exercise Price Range Two [Member] Exercise price range two. Operating lease liability Operating Lease, Liability, Current Current lease liability Finance lease right-of-use asset obtained in exchange for lease oblgations Right-of-Use Asset Obtained in Exchange for Finance Lease Liability Accumulated Deficit Retained Earnings [Member] Payments to Acquire Property, Plant, and Equipment, Total Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Document Transition Report Document Transition Report Eligible employees purchase common stock percentage of lower of fair market value Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent Lessee, Operating Lease, Liability, to be Paid, Year Two 2026 Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Proceeds from Stock Plans Proceeds from the issuance of common stock under ESPP Weighted average exercise price per share, Exercised Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Minimum Minimum [Member] Offering costs Incurred Offering costs Incurred Offering costs Common Stock Common Stock [Member] Restricted Cash, Total Restricted cash Restricted Cash weighted-average grant date fair value Weighted-average grant date fair value, Unvested balance at beginning of period Weighted-average grant date fair value, Unvested balance at end of period Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Noncash lease expense Operating Lease, Right-of-Use Asset, Periodic Reduction Additional Paid-in Capital Additional Paid-in Capital [Member] Fair value measurement, assets Marketable securities, Fair value Debt Securities, Available-for-Sale, Current Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Income Statement Location Statement of Income Location, Balance [Domain] Lessee, Operating Lease, Liability, to be Paid, Year One 2025 Pre-funded warrants. Pre-Funded Warrants [Member] Pre-Funded Warrants Total leased assets Leased Assets Leased assets. Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Accrued expenses and other liabilities Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Sales agreement remaining authorized amount. Sales Agreement Remaining Authorized Amount Amount remaining under the sales agreement Basis of presentation Basis of Accounting, Policy [Policy Text Block] Scenario Scenario [Domain] $11.73 - $88.98 Exercise Price Range Four [Member] Exercise price range four. Current lease liability Finance lease liability Finance Lease, Liability, Current License Agreement License Agreement [Member] License agreement. Common stock Common Stock, Value, Issued Participants accrue rights to purchase maximum common stock amount Participants Accrue Rights To Purchase Maximum Common Stock Amount Participants accrue rights to purchase maximum common stock amount. Prepaid rent Prepaid Rent Fair value measurement, assets Cash and Cash Equivalents, Fair Value Disclosure Agency Security. Agency Security [Member] Agency Securities Disbursement incurred costs for lab space Disbursement Incurred Costs For Lab Space Disbursement incurred costs for lab space. Lease liability Lease liability Operating Lease, Liability Measurement Frequency [Axis] Commitments (Note 8) Commitments and Contingencies Marketable Securities [Line Items] Marketable Securities [Line Items] Research and development Accrued Research And Development Liabilities Current Accrued research and development liabilities, current. Marketable Securities Marketable Securities [Member] Marketable securities. Weighted Average Number of Shares Outstanding, Diluted, Total Weighted average common shares outstanding, diluted Weighted Average Number of Shares Outstanding, Diluted Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Lease renewal period Lessee, Operating Lease, Renewal Term Total undiscounted lease payments Lessee, Operating Lease, Liability, to be Paid Offering costs in accounts payable Offering Costs In Accounts Payable Offering costs in accounts payable. Operating Lease Until December 30 2023 Operating Lease Until December 302023 [Member] Operating lease until december 302023 [member]. Lease liability Lease liability Finance Lease, Liability Entity Small Business Entity Small Business Terms of award Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award Chestnut Run Lease Chestnut Run Lease [Member] Chestnut run lease. Operating lease estimated incremental borrowing rate percent Operating Lease Estimated Incremental Borrowing Rate Percent Operating lease estimated incremental borrowing rate percent. Amortization of premium and discount on marketable securities, net Accretion (Amortization) of Discounts and Premiums, Investments Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows used in financing activities: Weighted average exercise price per share, Outstanding at beginning of period Weighted average exercise price per share, Outstanding at end of period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Number of marketable securities Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Shelf registration statement remaining amount Registration Arrangement, Remaining Amount Registration arrangement, remaining amount. Emerging Growth Company Status Emerging Growth Company Status [Policy Text Block] Emerging Growth Company Status. Operating lease right-of-use asset obtained in exchange for lease oblgations Operating lease right-of-use asset obtained in exchange for lease oblgations Operating lease right-of-use assets obtained in exchange for operating lease liabilities Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Measurement Frequency [Domain] Commitments Commitments Disclosure [Text Block] Reimbursements for development of lab space period Reimbursements For Development Of Lab Space Period Reimbursements for development of lab space period. Significant unobservable inputs (Level 3) Fair Value, Inputs, Level 3 [Member] Weighted-average remaining lease term, Operating lease (years) Operating Lease, Weighted Average Remaining Lease Term Subsequent Events [Text Block] Subsequent Events OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total Unrealized gain (loss) on marketable securities, net of tax Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Deferred Offering Costs Offering costs previously paid and deferred Short-Term Lease, Cost Short-term lease cost